Aviceda Publications
At Aviceda, we have developed an active and collaborative research department, with a core mission to advance the fundamental scientific understanding that underpins our clinical assets.
2024
Effect of Hypoxia on Siglec-7 and Siglec-9 Receptors and Sialoglycan Ligands and Impact of Their Targeting on NK Cell Cytotoxicity
Husam Nawafleh, Nagwa Zeinelabdin, Michelle K. Greene, PhD, Anitha Krishnan, PhD, Linus Ho, MD, PhD, Mohamed Genead, MD, Derek Kunimoto, MD, Christopher J. Scott, PhD, Michael J. Tolentino, MD, Salem Chouaib, PhD
Pharmaceuticals (Basel)
PolySialic Acid Nanoparticles Actuate Complement-Factor-H- Mediated Inhibition of the Alternative Complement Pathway: A Safer Potential Therapy for Age-Related Macular Degeneration
Sheri L. Peterson, PhD, Anitha Krishnan, PhD, Diyan Patel, MS, Amit Lad, PhD, Jutamas Shaughnessy, MD, PhD, Sanjay Ram, MD, David Callanan, MD, Derek Kunimoto, MD, Mohamed Genead, MD, Michael J. Tolentino, MD
Pharmaceuticals - MDPI
Comprehensive Ocular and Systemic Safety Evaluation of Polysialic Acid-Decorated Immune Modulating Therapeutic Nanoparticles (PolySia-NPs) to Support Entry into First-in-Human Clinical Trials
Anitha Krishnan, PhD, David Callanan, MD, Victor G. Sendra, PhD, Amit Lad, PhD, Sunny Christian, Ravinder Earla, PhD, Ali Khanehzar, PhD, Andrew J. Tolentino, BS, Valory Anne Sarmiento Vailoces, Michelle K. Greene, PhD, Christopher J. Scott, PhD, Derek Kunimoto, MD, Tarek Hassan, MD, Mohamed Genead, MD, Michael J. Tolentino, MD
Pharmaceuticals - MDPI
2023
Sialic Acid Mimetic Microglial Sialic Acid-Binding Immunoglobulin-like Lectin Agonism: Potential to Restore Retinal Homeostasis and Regain Visual Function in Age-Related Macular Degeneration
Michael J. Tolentino, MD, Andrew J. Tolentino, BS, Elizabeth M. Tolentino, Anitha Krishnan, PhD, Mohamed Genead, MD
Pharmaceuticals - MDPI
PolySialic acid-nanoparticles inhibit macrophage mediated inflammation through Siglec agonism: a potential treatment for age related macular degeneration
Anitha Krishnan, PhD, Victor G. Sendra, PhD, Diyan Patel, MS, Amit Lad, PhD, Michelle K. Greene, PhD, Peter Smyth, PhD, Samantha A. Gallaher, Úna M. Herron, PhD, Christopher J. Scott, PhD, Mohamed Genead, MD, Michael J. Tolentino, MD
Frontiers in Immunology
SIGLECs the Main Self-Pattern Recognition Receptors of the Immune System. A Promising Target for Inflammatory Modulation
Andrew J. Tolentino, BS, Michael J. Tolentino, MD, Elizabeth M. Tolentino, Anitha Krishnan, PhD, Mohamed Genead, MD
American Journal of Biomedical Science & Research
Glycoimmune Therapy as a Novel Treatment Approach for Geographic Atrophy
Sophie J. Bakri, MD, MBA, Jeffrey S. Heier, MD, Arshad M. Khanani, MD, Ma, FASRS, Baruch D. Kuppermann, MD, PhD, Carl D. Regillo, MD, FACS, FASRS, Peter K. Kaiser, MD, FASRS